The Coronary Artery Disease and Renal Failure (CAD-REF) registry: Trial design, methods, and aims

The CAD-REF registry will establish one of the largest ethnically homogeneous cohorts, to date, of clinically and angiographically well-characterized patients with CAD who have all stages of CKD. This approach offers great opportunities for an improved understanding of the underlying pathophysiologic mechanism and clinical impact of CKD in patients with CAD, especially including the identification of clinically relevant risk factors and (genetic and other bio-) markers as a basis to ameliorate future treatment strategies.