کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5928837 | 1167800 | 2013 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cardiac Safety Research ConsortiumThe evaluation and management of drug effects on cardiac conduction (PR and QRS Intervals) in clinical development
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cardiac Safety Research ConsortiumThe evaluation and management of drug effects on cardiac conduction (PR and QRS Intervals) in clinical development Cardiac Safety Research ConsortiumThe evaluation and management of drug effects on cardiac conduction (PR and QRS Intervals) in clinical development](/preview/png/5928837.png)
چکیده انگلیسی
Recent advances in electrocardiographic monitoring and waveform analysis have significantly improved the ability to detect drug-induced changes in cardiac repolarization manifested as changes in the QT/corrected QT interval. These advances have also improved the ability to detect drug-induced changes in cardiac conduction. This White Paper summarizes current opinion, reached by consensus among experts at the Cardiac Safety Research Consortium, on the assessment of electrocardiogram-based safety measurements of the PR and QRS intervals, representing atrioventricular and ventricular conduction, respectively, during drug development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Heart Journal - Volume 165, Issue 4, April 2013, Pages 489-500
Journal: American Heart Journal - Volume 165, Issue 4, April 2013, Pages 489-500
نویسندگان
Adel MD, MS, MFPM, Gary A. PhD, Robert MD, David E. MD, Christer MD, PhD, Eric L. MD, Colette PhD, Matthew MD, Mary Jane MD, PhD, Mónica L. MD, PhD, Luana Pesco MD, Glenn F. MD, Ignacio MD, Philip T. MD,