کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5930160 | 1572140 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparison of Outcomes After One-Versus-Two Transcatheter Aortic Valve Implantation During a Same Procedure (from the FRANCE2 Registry)
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Analysis of the causes, outcomes, and mortality of patients with severe symptomatic aortic stenosis requiring the implantation of 2 valves during transcatheter aortic valve implantation was conducted from the French Aortic National CoreValve and Edwards 2 (FRANCE2) registry. Pre- and postprocedural data from 3,919 patients from January 2010 to December 2011 (CoreValve or Edwards) were collated and analyzed. Characteristics of patients requiring immediate second valve procedures were compared with those of the other patients. The 72 patients (1.8%) who underwent implantation of a second valve were studied. Indications were device malpositioning (72%) and embolization (28%). Clinical and echocardiographic characteristics of patients receiving 2 valves were comparable with those of the other patients. The 2-year survival rate was 51.7% for patients with 2 valves as opposed to 62.3% for those with 1 valve (p <0.001). The need for a second valve was an independent predictor of all-cause (hazard ratio 2.32, 95% confidence interval 1.50 to 3.60, p <0.001) and cardiovascular (hazard ratio 2.64, 95% confidence interval 1.35 to 5.15, p <0.001) mortality at 2 years. During follow-up, clinical and echocardiographic data remained similar between the 2 groups. In conclusion, in the FRANCE2 study, the main causes for second valve implantation during the same procedure were malpositioning and embolization. Although the procedure was feasible, it was accompanied by excess mortality. Valve hemodynamic status was preserved during the course of follow-up.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Cardiology - Volume 115, Issue 9, 1 May 2015, Pages 1273-1280
Journal: The American Journal of Cardiology - Volume 115, Issue 9, 1 May 2015, Pages 1273-1280
نویسندگان
Guillaume MD, Bruno PhD, Andrea MD, Pascal MD, PhD, Martine MD, PhD, Marc MD, PhD, Helene MD, PhD, Bernard MD, PhD, Pascal MD, PhD, Emmanuel MD, PhD, Karine MD, Alain MD, PhD, Michel MD, Alain MD, PhD, Patrick MD, Jean MD, Géraud MD,