Formylation of Alcohol with Formic Acid under Solvent-Free and Neutral Conditions Catalyzed by Free I2 or I2 Generated in situ from Fe(NO3)3·9H2O/NaI

Different alcohols were formylated by formic acid under solvent-free conditions in the presence of iodine as the catalyst with good-to-high yields at room temperature. I2 generated in situ from Fe(NO3)3·9H2O/NaI also catalyzed the formylation of the alcohols under solvent-free conditions. This gives a green and efficient reaction at room temperature, in which the use of toxic and corrosive molecular I2 is avoided.

Free I2 or I2 generated in situ from Fe(NO3)3·9H2O/NaI efficiently catalyzed the formylation of various alcohols by formic acid, giving good to excellent yields under solvent-free conditions at room temperature.Figure optionsDownload as PowerPoint slide