کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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59536 | 1419463 | 2012 | 10 صفحه PDF | دانلود رایگان |

The multicomponent condensation of an aryl aldehyde, acetyl chloride, acetonitrile, and enolizable ketone as one-pot synthesis of β-acetamido ketones in high yields was investigated using commercial, non-corrosive, and environmentally benign Keggin and Wells-Dawson heteropolyacid catalysts. The best catalyst was H5PW10V2O40. The methodology used simple experimental conditions, and the short reaction times and high yields indicate it is a useful strategy for the large scale synthesis of β-acetamido ketones.
An efficient one-pot method for the synthesis of β-acetamido ketones by H5PW10V2O40 as an environmentally benign and recyclable catalyst is described. The catalyst afforded short reaction times and high to excellent yields.Figure optionsDownload as PowerPoint slide
Journal: Chinese Journal of Catalysis - Volume 33, Issues 4–6, April–June 2012, Pages 923–932