کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5967119 | 1576163 | 2015 | 9 صفحه PDF | دانلود رایگان |
ObjectiveTo evaluate whether an association exists between an inter-arm systolic blood pressure difference (sIAD) and all-cause and cardiovascular mortality.MethodsWe searched for cohort studies that evaluated the association of a sIAD and all-cause or cardiovascular mortality in the electronic databases Medline/PubMed and Embase (August 2014). Random effects models were used to calculate pooled hazard ratios (HRs) and 95% confidence intervals (CIs).ResultsNine cohort studies (4 prospective and 5 retrospective) enrolling 15,617 participants were included. The pooled HR of all-cause mortality for a sIAD of â¥Â 10 mm Hg was 1.53 (95% CI 1.14-2.06), and that for a sIAD of â¥Â 15 mm Hg was 1.46 (1.13-1.88). Pooled HRs of cardiovascular mortality were 2.21 (95% CI 1.52-3.21) for a sIAD of â¥Â 10 mm Hg, and 1.89 (1.32-2.69) for a sIAD of â¥Â 15 mm Hg. In the patient-based cohorts including hospital- and diabetes-based cohorts, both sIADs of â¥Â 10 and â¥Â 15 mm Hg were associated with increased all-cause (pooled HR 1.95, 95% CI 1.01-3.78 and 1.59, 1.06-2.38, respectively) and cardiovascular mortality (pooled HR 2.98, 95% CI 1.88-4.72 and 2.10, 1.07-4.13, respectively). In the community-based cohorts, however, only a sIAD of â¥Â 15 mm Hg was associated with increased cardiovascular mortality (pooled HR 1.94, 95 % CI 1.12-3.35).ConclusionsIn the patient populations, a sIAD of â¥Â 10 or of â¥Â 15 mm Hg could be a useful indictor for increased all-cause and cardiovascular mortality, and a sIAD of â¥Â 15 mm Hg might help to predict increased cardiovascular mortality in the community populations.
Journal: International Journal of Cardiology - Volume 189, 15 June 2015, Pages 211-219