Understanding the biocide action of poly(hexamethylene biguanide) using Langmuir monolayers of dipalmitoyl phosphatidylglycerol

- Poly(hexamethylene biguanide) (PHMB) adsorbs at the air-liquid interface.
- PHMB expands Langmuir monolayers of phosphatidylglycerol (DPPG).
- Hydrophobic interactions between PHMB and DPPG were identified.
- Dehydration of carbonyl groups from DPPG in the presence of PHMB was also found.