Thermodynamic insights into drug-surfactant interactions: Study of the interactions of naporxen, diclofenac sodium, neomycin, and lincomycin with hexadecytrimethylammonium bromide by using isothermal titration calorimetry

- Anti-inflammatory, antibiotic drugs interactions studied with HTAB micelles, monomers.
- Energetics of drug-surfactant interactions and partitioning in micelles addressed.
- Mechanism of drug partitioning addressed based on physico chemical properties.
- Results provide role of functional groups on drugs for partitioning in micelles.
- Such studies provide guidelines for targeted synthesis and effective drug delivery.