کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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59942 | 1419433 | 2015 | 5 صفحه PDF | دانلود رایگان |
Chitosan-supported succinic anhydride-cinchonine (CTS-SA-CN) was synthesized via a two-step route with succinic anhydride as the linker. The catalyst was used to promote the direct asymmetric aldol reaction between cyclohexanone and a variety of aromatic aldehydes in aqueous medium. Aldol adducts were obtained in excellent yields (up to 99%) and good enantioselectivities (up to 96% ee). The CTS-SA-CN catalyst was successfully recycled simply by filtration after use, and was reused 5 times without any significant loss of activity.
Graphical AbstractChitosan-supported succinic anhydride-cinchonine was conveniently synthesized. The organocatalyst catalyzed the direct asymmetric aldol reaction with excellent yields and good enantioselectivity in aqueous medium.Figure optionsDownload as PowerPoint slide
Journal: Chinese Journal of Catalysis - Volume 36, Issue 3, March 2015, Pages 367–371