کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
599427 1454275 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Osteoblastic cells trigger gate currents on nanocrystalline diamond transistor
ترجمه فارسی عنوان
سلولهای استئوبلاستیک باعث جریان در ترانزیستور الماس نانوبلال می شوند
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
چکیده انگلیسی


• For adhered SAOS-2 cells, nanocrystalline H-diamond transistors exhibit about 100× increased gate currents.
• After cell delamination the transistors return to original state.
• Triggering effect is attributed to ions released from cells due to the H-diamond surface vicinity.
• This well reproducible effect could be used for sensitive electrical detection of cell adhesion quality.

We show the influence of osteoblastic SAOS-2 cells on the transfer characteristics of nanocrystalline diamond solution-gated field-effect transistors (SGFET) prepared on glass substrates. Channels of these fully transparent SGFETs are realized by hydrogen termination of undoped diamond film. After cell cultivation, the transistors exhibit about 100× increased leakage currents (up to 10 nA). During and after the cell delamination, the transistors return to original gate currents. We propose a mechanism where this triggering effect is attributed to ions released from adhered cells, which depends on the cell adhesion morphology, and could be used for cell culture monitoring.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 129, 1 May 2015, Pages 95–99
نویسندگان
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