BSA/polyelectrolyte core-shell nanoparticles for controlled release of encapsulated ibuprofen

- BSA-based core-shell nanoparticles were developed as carrier system.
- The changes in protein's structure were studied by FT-IR and SAXS measurements.
- The self-assembly layers is composed of the oppositely charged polyelectrolytes.
- The polyelectrolyte shells slow down the release of the drug molecules.
- Kinetic models were used to describe the release mechanism.