Facilitating neural stem/progenitor cell niche calibration for neural lineage differentiation by polyelectrolyte multilayer films

- We fabricated a niche-modulated system to investigate bioeffects on NSPC differentiation.
- We can generate high percentage functional neurons without needed any growth factors.
- Neurite outgrowth lengths are more than 500 μm only after 3 days culture.
- Our results achieve important targets of neural engineering only by substrate induction.