Three-dimensional polycaprolactone scaffold via needleless electrospinning promotes cell proliferation and infiltration

- We fabricated fluffy three-dimensional PCL scaffold ultilizing disc-electrospinning.
- Disc-electrospun PCL had a higher production rate compared with needle electrospinning.
- The porous surface formed on disc-electrospun PCL fibers could effectively enhance protein adsorption.
- In vitro experiments show the disc-electrospun PCL scaffold could promote cell attachment, proliferation, and infiltration.