PST-Gold nanoparticle as an effective anticancer agent with immunomodulatory properties

► PST-Gold nanoparticle preparation using PST001 is a “green” nanoparticle synthesis. ► PST-Gold nanoparticles are stable over to a period of 1 year with a wide range of pH tolerance. ► PST-Gold nanoparticles induces cytotoxicity specifically against cancer cells through the induction of apoptosis. ► Administration of the nanoparticles was found to be devoid of any toxicity in BALB/c mice and human peripheral lymphocytes. ► PST-Gold nanoparticles exhibits significant immunomodulatory effects both in vitro and in vivo.