In vitro biocompatibility of magnetic thermo-responsive nanohydrogel particles of poly(N-isopropylacrylamide-co-acrylic acid) with Fe3O4 cores: Effect of particle size and chemical composition

► Magnetite/poly(N-isopropylacrylamide-co-acrylic acid) nanoparticles were prepared. ► These nanoparticles have magnetic functionality with thermo- and pH-responses. ► The synthesized nanoparticles demonstrated high (>98%) cell viability. ► High cell proliferation was associated with small size and low acrylic acid content.