کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6002900 1182988 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Crosstalk of the plasma contact system with bacteria
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Crosstalk of the plasma contact system with bacteria
چکیده انگلیسی
Activation of the plasma contact system triggers several cascade systems such as the kallikrein-kinin system, the intrinsic pathway of coagulation, the classical complement cascade and the fibrinolytic system. Recent studies have shown a critical role of the contact system for arterial and venous thrombus formation and thromboembolic disease. In contrast, the function of the contact system for host-defense reactions and its physiological functions have remained enigmatic. Experimental animal studies and clinical data have linked the contact system to bacterial infections with implications for sepsis disease. The present review summarizes the role of the contact system and its activation for bacterial infections.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thrombosis Research - Volume 130, Supplement 1, October 2012, Pages S78-S83
نویسندگان
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