کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6005171 | 1184660 | 2016 | 8 صفحه PDF | دانلود رایگان |
- A home-based tDCS treatment program can be safely administered by non-medical or research professionals given adequate teaching, ongoing communication, frequent feedback, and controlled device settings.
- Real tDCS after an induction period of five days of rTMS leads to better maintenance of rTMS induced benefits than sham tDCS after four-weeks of treatment for MdDS.
- The rate of skin irritation and overall side effect profile was low with self-administered tDCS.
- tDCS may be a reasonable primary or adjunctive treatment in MdDS and may avoid the need for travel, which can potentially exacerbate this syndrome.
BackgroundMal de debarquement syndrome is a medically refractory disorder characterized by chronic rocking dizziness that occurs after exposure to passive motion. Repetitive transcranial magnetic stimulation (rTMS) can acutely suppress the rocking dizziness but treatment options that extend the benefit of rTMS are needed.Objectives1) To determine whether transcranial direct current stimulation (tDCS) added after rTMS can extend the benefit of rTMS; 2) to determine whether participants can safely perform tDCS at home.MethodsParticipants were given five days of rTMS (1âHz right DLPFC/10âHz left DLPFC in right-handers, vice versa in left-handers), according to a previously piloted protocol. They received three days of training on tDCS self-administration and were then randomized to either real or sham tDCS for four-weeks (anode left DLPFC/cathode right DLPFC for right-handers, vice versa for left-handers).ResultsTwenty-three participants completed the study. Those who received real tDCS after rTMS showed significant improvements in the degree of rocking perception as measured by the MdDS Balance Rating Scale and anxiety ratings by Week 4 of tDCS and a trend for improvement on the Dizziness Handicap Inventory. Two rTMS non-responders responded well to subsequent open-label tDCS. Side effects were mild and not different between real and sham tDCS. There were no episodes of skin burns in a group total of 556 sessions of tDCS. Satisfaction was rated high.ConclusionsHome-based tDCS can be performed safely and may be beneficial in selected individuals. Adequate teaching, automatic device safety features, and a good communications infrastructure are components of successful home therapy.
Journal: Brain Stimulation - Volume 9, Issue 4, JulyâAugust 2016, Pages 537-544