Nano-formulation of paclitaxel by vitamin E succinate functionalized pluronic micelles for enhanced encapsulation, stability and cytotoxicity

► Tocopheryl succinate modified pluronic micelles were prepared for drug delivery. ► Resultant micelles of paclitaxel showed enhanced encapsulation efficiency. ► Pluronic micelles could be modified to have improved tumor specific toxicity. ► Micelles could be modified to have slower plasma elimination rate.