Synthesis and immobilization of micro-scale drug particles in presence of β-cyclodextrins

► Anti-solvent synthesis of micro drug particle and subsequent film formation are presented. ► β-cyclodextrins were capable of inhibiting particle growth and stabilize the drug particles. ► Hydroxypropyl-β-cyclodextrin was found to be most effective in reducing the particle size. ► The drug release showed improvement in release rate due to drug/cyclodextrin interactions.