Interaction of chlorhexidine with biomembrane models on glass ionomer by using the Langmuir-Blodgett technique

► Chlorhexidine interacts with Langmuir monolayers as bacteria cell membrane models. ► Surface pressure isotherms changes with chlorhexidine. ► Infrared spectroscopy shows that lipids and proteins are affected. ► Membrane is transferred to glass ionomers as LB films. ► Effect of chlorhexidine is evaluated.