Pluronic-Nanogold hybrids: Synthesis and tagging with photosensitizing molecules

► Synthesis of Pluronic-Nanogold hybrids in a single step. ► The prepared nanohybrids are stable in high molarity NaCl solution. ► Formation of multifunctional Methylene Blue tagged Pluronic-Nanogold hybrids (Au-PF127-MB). ► Assessment of Au-PF127-MB as combined SERS and fluorescent tags. ► Methylene Blue mediated singlet oxygen generation.