کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
600721 1454307 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of nanosized porous hydroxyapatite granules in hydrogel by electrophoresis
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Synthesis of nanosized porous hydroxyapatite granules in hydrogel by electrophoresis
چکیده انگلیسی

Nanosized porous hydroxyapatite (HA) granules are expected to be useful as DNA and drug carriers for cells. We attempted to synthesize nanosized HA granules in an agarose gel by electrophoresis of calcium and phosphate ions. Wells were prepared on an agarose gel, and a CaCl2 solution was placed in the wells on the positive side and a Na2HPO4 solution was placed in the wells on the negative side. After a potential was applied, white precipitates appeared in the gel. The precipitates were calcium-deficient HA granules of approximately 300–600 nm in diameter. These granules were composed of fiber-like particles and had a porous structure. The diameters of the granules were decreased by an increase in the gel concentration. Hence, we successfully synthesized nanosized porous HA granules to be used as DNA and drug carriers.

Figure optionsDownload as PowerPoint slideHighlights
► Nanosized HA granules were synthesized in an agarose gel by electrophoresis.
► The HA granules were approximately 300–600 nm in diameter.
► The HA granules were composed of fiber-like particles and had a porous structure.
► The HA granules had calcium-deficient compositions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 97, 1 September 2012, Pages 236–239
نویسندگان
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