کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
600854 1454310 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bovine serum albumin film as a template for controlled nanopancake and nanobubble formation: In situ atomic force microscopy and nanolithography study
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Bovine serum albumin film as a template for controlled nanopancake and nanobubble formation: In situ atomic force microscopy and nanolithography study
چکیده انگلیسی

Air nanobubbles and nanopancakes were investigated in situ by both tapping mode atomic force microscopy (TM AFM) and atomic force nanolithography techniques employing bovine serum albumin (BSA) film supported by highly oriented pyrolytic graphite (HOPG). The BSA denaturation induced by the water-to-ethanol exchange served for conservation of nanobubble and nanopancake sites appearing as imprints in BSA film left by gaseous cavities formerly present on the interface in the aqueous environment. Once the BSA film was gently removed by the nanoshaving technique applied in ethanol, a clean basal plane HOPG area with well-defined dimensions was regenerated. The subsequent reverse ethanol-to-water exchange led to the re-formation of nanopancakes specifically at the nanoshaved area. Our approach paves the way for the study of gaseous nanostructures with defined dimensions, formed at solid–liquid interface under controlled conditions.

Figure optionsDownload as PowerPoint slideHighlights
► Nanobubbles and nanopancakes influence the protein adsorption.
► Atomic force nanolithography allows the patterning of protein layer.
► Fabrication of gaseous nanocavities of controlled dimensions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 94, 1 June 2012, Pages 213–219
نویسندگان
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