The phenotypic response of bovine corneal endothelial cells on chitosan/polycaprolactone blends

► Both chitosan and PCL have been approved by Food and Drug Administration (FDA) as biodegradable biomaterials. ► A new blended material from chitosan and PCL to maintain viability and stimulate ECM production of CECs concurrently. ► Transparency can be maintained and measured cellular proliferative ability outcomes suggest good propagation capacity. ► BCECs can preserve phenotypes and produce ECM proteins on chitosan/PCL blends.