Effect of d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) on surfactant monolayers

► TPGS addition to surfactant monolayers leads to low surface tensions of 1-2 mN/m. ► TPGS addition maintains airway patency. ► TPGS acts as an antioxidant. ► TPGS can be an adjuvant to pulmonary surfactants.