کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6015546 | 1186070 | 2014 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Magnetic resonance volumetry of the hippocampus in familial spontaneous epileptic cats
ترجمه فارسی عنوان
حجم سنجی رزونانس مغناطیسی هیپوکامپ در گربه های صرع خودبخودی خانوادگی
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کلمات کلیدی
T2wMTLEFSEHippocampal volumetryT2-weighted - T2 وزنfast spin echo - اسپین اسپین سریعhippocampal sclerosis - اسکلروز هیپوکامپ FLAIR - اشتباهMRI - امآرآی یا تصویرسازی تشدید مغناطیسیfluid-attenuated inversion recovery - بازیابی معکوس مایعHippocampal volume - حجم هیپوکامپmesial temporal epilepsy - صرع زمانی مسیالmesial temporal lobe epilepsy - صرع لوب صرع مزیالgenetic epilepsy - صرع ژنتیکیAnimal model - مدل حیوانیCats - گربه
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
چکیده انگلیسی
A strain of familial spontaneous epileptic cats (FSECs) with typical limbic seizures was identified in 2010. The electroencephalographic features suggested that an epileptogenic zone is present in the mesial temporal structures (i.e., amygdala and/or hippocampus). In this study, visual evaluations and quantitative analyses were performed by using 3D MR hippocampal volumetry in comparing FSECs with age-matched controls. Visual hippocampal asymmetries were seen in 8 of 14 (57.1%) FSECs. The FSEC group showed a significantly higher asymmetric ratio (4.15%) than the control group (0.99%). The smaller side of hippocampal volume (HV) (0.206Â cm3) in FSECs was significantly smaller than the mean HV in controls (0.227Â cm3). However, the means of left and right HVs and total HVs in FSECs showed no differences because the laterality of hippocampal atrophy was different in each individual. Therefore, since FSECs represent a true model of spontaneous epilepsy, hippocampal volumetry should be evaluated in each individual as well as in human patients. The significant asymmetry of HV suggests the potential for hippocampal atrophy in FSECs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy Research - Volume 108, Issue 10, December 2014, Pages 1940-1944
Journal: Epilepsy Research - Volume 108, Issue 10, December 2014, Pages 1940-1944
نویسندگان
Shunta Mizoguchi, Daisuke Hasegawa, Takayuki Kuwabara, Yuji Hamamoto, Fukie Ogawa, Aki Fujiwara, Naoaki Matsuki, Michio Fujita,