کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6015570 1186073 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Low potency and limited efficacy of antiepileptic drugs in the mouse 6 Hz corneal kindling model
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Low potency and limited efficacy of antiepileptic drugs in the mouse 6 Hz corneal kindling model
چکیده انگلیسی
We can conclude that 6 Hz kindling may be more advantageous than the previously described 50/60 Hz corneal kindling models due to its robustness and persistence of the fully kindled state. Furthermore, the observed low potency and limited efficacy of AEDs in 6 Hz fully kindled mice suggest that this model could be a useful tool in the discovery of novel AEDs targeting treatment resistant epilepsy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy Research - Volume 108, Issue 4, May 2014, Pages 675-683
نویسندگان
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