کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6020502 1580413 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
IL-22 secreting CD4 + T cells in the patients with neuromyelitis optica and multiple sclerosis
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
IL-22 secreting CD4 + T cells in the patients with neuromyelitis optica and multiple sclerosis
چکیده انگلیسی

Interleukin (IL)-22 secreting CD4+ T (Th22) cells and IL-22 are involved in the pathogenesis of autoimmune disease, but their role in neuromyelitis optica (NMO) and multiple sclerosis (MS) is unclear. We measured the proportion of Th22, Th17, CD4+IL-22+IL-17A+ T cells and serum IL-22 in NMO and MS patients. The proportion of Th22 cells, Th17 cells and serum IL-22 were increased in patients with NMO and MS. Our findings suggest that increased Th22 cells may play an important role in the pathogenesis of NMO and MS.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 261, Issues 1–2, 15 August 2013, Pages 87-91
نویسندگان
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