Spectratype analysis of clonal T cell expansion in murine experimental stroke

► We investigated clonal T cell expansion in experimental stroke. ► Spectratype analysis was used to detect T cell receptor repertoire diversity. ► We detected T cell expansion in brains at 7 days and 14 days after stroke. ► Clonal expansion was also observed to a lesser extent in spleens and lymph nodes. ► This is the first study directly showing clonal T cell expansion after stroke.