کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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602146 | 879964 | 2009 | 7 صفحه PDF | دانلود رایگان |
The vital bioactivities of bile salts are physiologically important molecules. The concept of using bile acids and their conjugates in nanoscience is a novel idea, which opens up fascinating prospects and gives way for various versatile properties. Here in, we report novel strategy for the synthesis of aqueous stable, silver and gold nanoparticles (Ag & AuNPs) using naturally occurring amino acid conjugated sodium salt of taurocholate (NaTC) and glycocholate (NaGC) as reducing and capping agents. The formation of nanoparticles was kinetically monitored using UV–vis spectroscopy at different time intervals. It was noticed, that the rate of reduction of AgNO3 is much faster than the HAuCl4 at fixed concentration of bile salts. Furthermore, the size and shape of the NPs are controlled and achieved by changing the nature of bile salts. The synthesized nanoparticles were characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD) techniques for morphological studies. The interaction between nanoparticles with bile salts was investigated using FT-IR spectroscopy, cyclic voltammetry (CV) and thermogravimetric analysis (TGA).
Journal: Colloids and Surfaces B: Biointerfaces - Volume 73, Issue 2, 15 October 2009, Pages 387–393