کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
602162 | 879965 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of bone formation deriving biosilanes
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
شیمی کلوئیدی و سطحی
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چکیده انگلیسی
Six silane coupling agents having amide group (biosilanes) were synthesized with the aim to construct the material surface that allows cells to be compatible with it without their destruction. These agents were expected to make a soft landing to cytoplasm through the hydrogen bonding between their amide groups and cells. Evaluations of cell affinity using glass substrates modified with the synthesized biosilanes revealed that many cells remain on the modified glass plate. In addition, the implantation into the body of immunodeficient mouse of a composite material composed of porous hydroxyapatite and osteoblast showed the formation of a bone-like structure.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 66, Issue 1, 1 October 2008, Pages 71–76
Journal: Colloids and Surfaces B: Biointerfaces - Volume 66, Issue 1, 1 October 2008, Pages 71–76
نویسندگان
Norio Yoshino, Kaori Nakajima, Keisuke Nakamura, Yukishige Kondo, Katsura Ohashi, Tomotaro Nihei, Masahiro Saito, Toshio Teranaka,