کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
602208 879967 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation and characterization of amino-functionalized magnetic nanogels via photopolymerization for MRI applications
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Preparation and characterization of amino-functionalized magnetic nanogels via photopolymerization for MRI applications
چکیده انگلیسی

To design peptide-targeted iron oxide as magnetic resonance imaging (MRI) contrast agents, amino-functionalized magnetic nanogels were prepared by using N-(2-aminoethyl) methacrylamide hydrochloride (AEM·HCl) as monomer via new photochemical approach. Their chemical structure and composition were characterized by Fourier transform infrared spectra (FTIR) and thermogravimetric analyses (TGA). The core–shell structure of magnetic nanogels was confirmed by high-resolution transmission electron microscopy (HRTEM). The good storage stability, high magnetic content (88.7%), high saturation magnetizations and superparamagnetic behavior suggested their great potentials as MRI contrast agents, which were confirmed by their measurements of r2 and coronal image of the crossing of mouse kidney.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 71, Issue 2, 1 July 2009, Pages 243–247
نویسندگان
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