کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6023080 | 1580865 | 2016 | 35 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
High-definition tDCS alters impulsivity in a baseline-dependent manner
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
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چکیده انگلیسی
In intertemporal choice (ITC), people discount future rewards in proportion to the time delay until reward receipt. Despite recent non-invasive brain stimulation studies suggesting a general causal link between dorsolateral prefrontal cortex (dlPFC) activity and ITC impulsivity, results regarding the functional specificity of dlPFC are mixed. We used high-definition transcranial direct current stimulation (HD-tDCS) to map changes in causal impulsivity through bi-directional modulation of left and right dlPFC during ITC. Model-free and model-based analyses demonstrated that anodal and cathodal stimulation of left dlPFC, but not right dlPFC, decreased and increased impulsivity, respectively. Critically, an individual differences analysis revealed that modulation of impulsivity was contingent on participants' baseline impulsivity. Overall, our results might reconcile the discrepancies in the existing literature and suggest a baseline-dependent role for left dlPFC during ITC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 143, December 2016, Pages 343-352
Journal: NeuroImage - Volume 143, December 2016, Pages 343-352
نویسندگان
Bo Shen, Yunlu Yin, Jiashu Wang, Xiaolin Zhou, Samuel M. McClure, Jian Li,