کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6023337 1580874 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An a contrario approach for the detection of patient-specific brain perfusion abnormalities with arterial spin labelling
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
An a contrario approach for the detection of patient-specific brain perfusion abnormalities with arterial spin labelling
چکیده انگلیسی

In this paper, we introduce a new locally multivariate procedure to quantitatively extract voxel-wise patterns of abnormal perfusion in individual patients. This a contrario approach uses a multivariate metric from the computer vision community that is suitable to detect abnormalities even in the presence of closeby hypo- and hyper-perfusions. This method takes into account local information without applying Gaussian smoothing to the data. Furthermore, to improve on the standard a contrario approach, which assumes white noise, we introduce an updated a contrario approach that takes into account the spatial coherency of the noise in the probability estimation.Validation is undertaken on a dataset of 25 patients diagnosed with brain tumours and 61 healthy volunteers. We show how the a contrario approach outperforms the massively univariate general linear model usually employed for this type of analysis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 134, 1 July 2016, Pages 424-433
نویسندگان
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