کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
602498 | 879979 | 2008 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Temperature effect on nanometer-scale physical properties of mixed phospholipid monolayers Temperature effect on nanometer-scale physical properties of mixed phospholipid monolayers](/preview/png/602498.png)
Mixed dipalmitoylphosphatidylcholine (DPPC) and dioleoylphosphatidylcholine (DOPC) monolayers have been deposited on mica using Langmuir–Blodgett technique, as a model system for biomembranes. Nanometer-scale surface physical properties were quantitatively characterized with the gradual temperature change using the atomic force microscope. At 25 °C, tapping mode imaging revealed the clear phase-separation in the form of microscopic DPPC domain embedded in a DOPC matrix and the obvious step height between the higher DPPC phase and the lower DOPC phase. Surface force measurement made at 25 °C in contact mode showed significant contrasts in deformation elasticity, adhesion, and jump-to-surface. These physical property differences were kept below 40 °C, while they almost disappeared over 40 °C. In addition, the reversibility of the properties for the temperature change was also found.
Journal: Colloids and Surfaces B: Biointerfaces - Volume 62, Issue 1, 15 March 2008, Pages 157–161