کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6025665 1580898 2015 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cortical structural abnormalities in very preterm children at 7 years of age
ترجمه فارسی عنوان
ناهنجاری های ساختاری کوریک در کودکان بسیار زودرس در 7 سالگی و یک ساله
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی
We analyzed long-lasting alterations in brain morphometry associated with preterm birth using volumetric and surface-based analyses applied to children at age 7 years. Comparison of 24 children born very preterm (VPT) to 24 healthy term-born children revealed reductions in total cortical gray matter volume, white matter volume, cortical surface area and gyrification index. Regional cortical shape abnormalities in VPT children included the following: shallower anterior superior temporal sulci, smaller relative surface area in the inferior sensori-motor cortex and posterior superior temporal cortex, larger relative surface area and a cingulate sulcus that was shorter or more interrupted in medial frontoparietal cortex. These findings indicate a complex pattern of regional vulnerabilities in brain development that may contribute to the diverse and long-lasting neurobehavioral consequences that can occur after very premature birth.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 109, 1 April 2015, Pages 469-479
نویسندگان
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