کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6028316 1580921 2013 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Automatic magnetic resonance spinal cord segmentation with topology constraints for variable fields of view
ترجمه فارسی عنوان
تقسیم بندی مغناطیسی با محدودیت توپولوژی برای زمینه های متغیر دید
کلمات کلیدی
ساخت و ساز اطلس، تقسیم بندی با حفظ توپولوژی، هومورفیسم دیجیتال، تقسیم بندی نخاع، تصویربرداری رزونانس مغناطیسی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی
Spinal cord segmentation is an important step in the analysis of neurological diseases such as multiple sclerosis. Several studies have shown correlations between disease progression and metrics relating to spinal cord atrophy and shape changes. Current practices primarily involve segmenting the spinal cord manually or semi-automatically, which can be inconsistent and time-consuming for large datasets. An automatic method that segments the spinal cord and cerebrospinal fluid from magnetic resonance images is presented. The method uses a deformable atlas and topology constraints to produce results that are robust to noise and artifacts. The method is designed to be easily extended to new data with different modalities, resolutions, and fields of view. Validation was performed on two distinct datasets. The first consists of magnetization transfer-prepared T2*-weighted gradient-echo MRI centered only on the cervical vertebrae (C1-C5). The second consists of T1-weighted MRI that covers both the cervical and portions of the thoracic vertebrae (C1-T4). Results were found to be highly accurate in comparison to manual segmentations. A pilot study was carried out to demonstrate the potential utility of this new method for research and clinical studies of multiple sclerosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 83, December 2013, Pages 1051-1062
نویسندگان
, , , , , , ,