کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6028673 1580924 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The human connectome: Origins and challenges
ترجمه فارسی عنوان
ارتباط انسانی: ریشه ها و چالش ها
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی


- The connectome offers a structural basis for brain function.
- The connectome has parallel origins in cognitive as well as cellular neuroscience.
- Network science is important for modeling and analyzing connectome data sets.
- Challenges include variability, plasticity and multi-scale organization.
- An emerging research focus aims at relating structural to functional connectivity.

The human connectome refers to a map of the brain's structural connections, rendered as a connection matrix or network. This article attempts to trace some of the historical origins of the connectome, in the process clarifying its definition and scope, as well as its putative role in illuminating brain function. Current efforts to map the connectome face a number of significant challenges, including the issue of capturing network connectivity across multiple spatial scales, accounting for individual variability and structural plasticity, as well as clarifying the role of the connectome in shaping brain dynamics. Throughout, the article argues that these challenges require the development of new approaches for the statistical analysis and computational modeling of brain network data, and greater collaboration across disciplinary boundaries, especially with researchers in complex systems and network science.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 80, 15 October 2013, Pages 53-61
نویسندگان
,