کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
602969 880004 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
XPS investigation of DNA binding to zirconium-phosphonate surfaces
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
XPS investigation of DNA binding to zirconium-phosphonate surfaces
چکیده انگلیسی

The surface coverage of phosphorylated oligonucleotides immobilized on a zirconium-phosphonate surface was analyzed using X-ray photoelectron spectroscopy (XPS). By quantifying the intensity of the N 1s signal originating from the oligonucleotide and the Zr 3d peak from the metal-phosphonate surface, the surface coverage of the oligonucleotide could be calculated with a modified substrate-overlayer model. We found relatively low surface coverages indicating that once covalently bound via the terminal phosphate the polymer chain further physisorbs to the surface limiting the adsorption of additional molecules.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 58, Issue 1, 1 July 2007, Pages 34–38
نویسندگان
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