The emergence of abnormal hypersynchronization in the anatomical structural network of human brain

► The role of structural connectivity in abnormal hypersynchronization is studied. ► Oscillatory dynamics are simulated on a biologically realistic brain network. ► The emergence of hypersynchronization relies on connectivity strength and delay. ► Hypersynchronization tends to occur only at low frequencies. ► Hypersynchronization has a clear anterior origin involving areas of frontal lobe.