Mapping interictal epileptic discharges using mutual information between concurrent EEG and fMRI

► Use of Mutual Information to study interictal epileptic discharges with EEG-fMRI. ► Balance between modalities with no assumptions of linearity, HRF shape or gaussianity. ► Evaluated in 14 patients with focal epilepsy and compared with two GLM-based models. ► Adds clinically relevant information and supports main GLM assumptions for IED.