Functional imaging of brain responses to different outcomes of hypothesis testing: revealed in a category induction task

Functional magnetic resonance imaging (fMRI) was used to examine differences in brain activation that occur when a person receives the different outcomes of hypothesis testing (HT). Participants were provided with a series of images of batteries and were asked to learn a rule governing what kinds of batteries were charged. Within each trial, the first two charged batteries were sequentially displayed, and participants would generate a preliminary hypothesis based on the perceptual comparison. Next, a third battery that served to strengthen, reject, or was irrelevant to the preliminary hypothesis was displayed. The fMRI results revealed that (1) no significant differences in brain activation were found between the 2 hypothesis-maintain conditions (i.e., strengthen and irrelevant conditions); and (2) compared with the hypothesis-maintain conditions, the hypothesis-reject condition activated the left medial frontal cortex, bilateral putamen, left parietal cortex, and right cerebellum. These findings are discussed in terms of the neural correlates of the subcomponents of HT and working memory manipulation.

► LaCoO3 and LaMnO3 are not completely miscible. ► Oxidation enthalpies are - 680 ± 40 and - 522 ± 40 kJ(molO2)-1 for x = 0.25 and 0.75. ► Enthalpies of oxidation do not vary significantly with oxygen stoichiometry.