Neuromagnetic index of hemispheric asymmetry predicting long-term outcome in sudden hearing loss

► Initial I/Camplitude on affected-ear stimulation predicted final hearing in ISSNHL. ► Our finding showed dynamics of top-down relationship in auditory pathway. ► Our finding showed a clinically relevant measure to predict final hearing of ISSNHL. ► Our finding showed a linkage between central plasticity and cochlear lesion. ► Our finding suggests a new perspective and intervention to diagnose and treat ISSNHL.