Deep brain stimulation induces BOLD activation in motor and non-motor networks: An fMRI comparison study of STN and EN/GPi DBS in large animals

► First report to set up a fMRI group analysis method for pigs ► STN vs EN/GPi stimulation show common sensorimotor network activation. ► PCA data also show that each target activates a distinctive neural network. ► Swine model may be a useful platform for global neuromodulatory DBS studies.