Quantitative measurement of cerebral physiology using respiratory-calibrated MRI

► We introduce a new MRI method of measuring neurophysiology. ► A model of BOLD FMRI is used to calculate OEF and CMRO2. ► We use a respiratory technique to provide the model with data. ► Quantitative images of cerebrovascular parameters are created from a single scan. ► The values obtained are in excellent agreement with other modalities and methods.