Automated delineation of white matter fiber tracts with a multiple region-of-interest approach

► Automated detection of the brain's white matter tracts. ► Implemented multiple-region-of-interest strategy using various automated algorithms. ► Tested three different image modalities for inter-subject, non-rigid registration. ► Superior results using tensor modality over T1-weighted or fractional anisotropy. ► Superior automated tracts using novel consensus label map fusion STAPLE algorithm.