DTI registration in atlas based fiber analysis of infantile Krabbe disease

► Performance evaluation of linear and seven non-linear DTI registration algorithms. ► Affine, B-spline, FSL-B-spline, Demons, Demons-log, MedINRIA, DTI-TK. ► Regional matching quality criterion. ► Fiber property profile (fractional anisotrophy) based criterion. ► DTI-TK registration method shows the best performance for our application.