Study factors influencing ventricular enlargement in schizophrenia: A 20Â year follow-up meta-analysis

► A meta-analysis of ventricular size studies of schizophrenic to normal subjects. ► This was a 20-year follow-up to a similar meta-analysis published in 1992. ► We drew 72 studies from the peer reviewed literature from 1979 to 2010. ► Our results showed significance between groups in ventricular size values. ► Factors related to how studies were conducted also predicted group differences.