Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS

► Mouse-specific technically innovative, high-sensitive MEMRI protocol. ► Detailed species-specific analysis on tracer concentrations and pharmacokinetics. ► Functional and histological toxicity of MnCl2 in single and serial applications. ► Proof of protocol in CNS models of neurode- and regeneration. ► Implications for long-term studies and use on genetically engineered mice.