A prior feature SVM-MRF based method for mouse brain segmentation

► A new method called pSVMRF is proposed for 3D mouse brain segmentation. ► The proposed pSVMRF outperforms existing methods in terms of accuracy. ► pSVMRF is more computationally efficient comparing to published eMRF. ► pSVMRF has the potential to handle extra high resolution mouse brain images. ► pSVMRF is capable to segment mutant mice brain images.